Stac gets the skeletal L-type calcium channel unstuck.
نویسنده
چکیده
Commentary to: Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca²⁺ channels. (Proc. Natl. Acad. Sci. 2015, pp. 602-606).
منابع مشابه
STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation
The adaptor proteins STAC1, STAC2, and STAC3 represent a newly identified family of regulators of voltage-gated calcium channel (CaV) trafficking and function. The skeletal muscle isoform STAC3 is essential for excitation-contraction coupling and its mutation causes severe muscle disease. Recently, two distinct molecular domains in STAC3 were identified, necessary for its functional interaction...
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ورودعنوان ژورنال:
- General physiology and biophysics
دوره 34 2 شماره
صفحات -
تاریخ انتشار 2015